PressPurt - Indeterminacy of Networks via Press Perturbations
This is a computational package designed to identify the
most sensitive interactions within a network which must be
estimated most accurately in order to produce qualitatively
robust predictions to a press perturbation. This is
accomplished by enumerating the number of sign switches (and
their magnitude) in the net effects matrix when an edge
experiences uncertainty. The package produces data and
visualizations when uncertainty is associated to one or more
edges in the network and according to a variety of
distributions. The software requires the network to be
described by a system of differential equations but only
requires as input a numerical Jacobian matrix evaluated at an
equilibrium point. This package is based on Koslicki, D., &
Novak, M. (2017) <doi:10.1007/s00285-017-1163-0>.